-Genomic Data for CSL Links
Protein
CSL
UniPROBE Accession Number
UP00484
Species
Homo sapiens
Domain
LAG1-DNAbind
Swiss-Prot
Q06330
Name and Synonyms
Name: recombination signal binding protein for immunoglobulin kappa J region.
Synonyms:SUH; csl; CBF1; KBF2; RBPJ; RBP-J; RBPJK; IGKJRB; RBPSUH; IGKJRB1; MGC61669
IHOP
89405
NCBI RefSeq
NP_976028.1
Description
Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcriptio
JASPAR
None Available
-PBM Motif Data for GST-CSL-NOTCH1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
CGTGGGAA E.S. 0.498
TTCCCACG E.S. 0.498
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NNVTGDGAVN
NBTCHCABNN
Downloads
Download the zip of all GST-CSL-NOTCH1 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for GST-CSL_Fig2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
CGTGGGAA E.S. 0.498
TTCCCACG E.S. 0.498
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NNVTGDGAVN
NBTCHCABNN
Downloads
Download the zip of all GST-CSL_Fig2 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for GST-CSL_Fig4
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
CGTGGGAA E.S. 0.499
TTCCCACG E.S. 0.499
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NNVTGDGARN
NYTCHCABNN
Downloads
Download the zip of all GST-CSL_Fig4 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for GST-NOTCH1_CSL-6His
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
C.TGGGAAC E.S. 0.495
GTTCCCA.G E.S. 0.495
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NNVTGDGARN
NYTCHCABNN
Downloads
Download the zip of all GST-NOTCH1_CSL-6His PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for GST-NOTCH1_CSL-6His_MAML1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
CGTGGGAA E.S. 0.497
TTCCCACG E.S. 0.497
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NNVTGDGARN
NYTCHCABNN
Downloads
Download the zip of all GST-NOTCH1_CSL-6His_MAML1 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for MAML1-CSL-GST-NOTCH1_Fig5
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
C.TGGGAA.C E.S. 0.493
G.TTCCCA.G E.S. 0.493
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NBVTGRGAAH
DTTCYCABVN
Downloads
Download the zip of all MAML1-CSL-GST-NOTCH1_Fig5 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for MAML1-CSL-GST-NOTCH1_Fig2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
C.TGGGAAC E.S. 0.498
GTTCCCA.G E.S. 0.498
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NNTGDGAVNN
NNBTCHCANN
Downloads
Download the zip of all MAML1-CSL-GST-NOTCH1_Fig2 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for MAML1-CSL-GST-NOTCH2_FigS1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
C..TGGGAAC E.S. 0.495
GTTCCCA..G E.S. 0.495
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NNVTGDGARN
NYTCHCABNN
Downloads
Download the zip of all MAML1-CSL-GST-NOTCH2_FigS1 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for MAML1-CSL-GST-NOTCH2_Fig5
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
CC.TGGGAA E.S. 0.492
TTCCCA.GG E.S. 0.492
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NBVTGRGAAH
DTTCYCABVN
Downloads
Download the zip of all MAML1-CSL-GST-NOTCH2_Fig5 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for MAML1-CSL-GST-NOTCH3
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
CC.TGGGAA E.S. 0.494
TTCCCA.GG E.S. 0.494
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NBVTGRGAAH
DTTCYCABVN
Downloads
Download the zip of all MAML1-CSL-GST-NOTCH3 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for MAML1-CSL-GST-NOTCH4
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
C..TGGGAAC E.S. 0.496
GTTCCCA..G E.S. 0.496
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
Save
Consensus
NNVTGDGAVN
NBTCHCABNN
Downloads
Download the zip of all MAML1-CSL-GST-NOTCH4 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-CSL Datasets
Complex Name Save View
GST-CSL-NOTCH1 save view
Run name PBM version Save View
GST-CSL-NOTCH1 AMADID # 015681 save view
Complex Name Save View
GST-CSL save view
Run name PBM version Save View
GST-CSL_Fig2 AMADID # 015681 save view
GST-CSL_Fig4 AMADID # 015681 save view
Complex Name Save View
GST-NOTCH1_CSL-6His save view
Run name PBM version Save View
GST-NOTCH1_CSL-6His AMADID # 015681 save view
Complex Name Save View
GST-NOTCH1_CSL-6His_MAML1 save view
Run name PBM version Save View
GST-NOTCH1_CSL-6His_MAML1 AMADID # 015681 save view
Complex Name Save View
MAML1-CSL-GST-NOTCH1 save view
Run name PBM version Save View
MAML1-CSL-GST-NOTCH1_Fig5 AMADID # 015681 save view
MAML1-CSL-GST-NOTCH1_Fig2 AMADID # 015681 save view
Complex Name Save View
MAML1-CSL-GST-NOTCH2 save view
Run name PBM version Save View
MAML1-CSL-GST-NOTCH2_FigS1 AMADID # 015681 save view
MAML1-CSL-GST-NOTCH2_Fig5 AMADID # 015681 save view
Complex Name Save View
MAML1-CSL-GST-NOTCH3 save view
Run name PBM version Save View
MAML1-CSL-GST-NOTCH3 AMADID # 015681 save view
Complex Name Save View
MAML1-CSL-GST-NOTCH4 save view
Run name PBM version Save View
MAML1-CSL-GST-NOTCH4 AMADID # 015681 save view
Gene Clone Type Last Modified Save View
CSL Not full length 2014-08-13 N/A N/A
Insert Sequence
1    ERPPPKRLTR EAMRNYLKER GDQTVLILHA KVAQKSYGNE KRFFCPPPCV
51   YLMGSGWKKK KEQMERDGCS EQESQPCAFI GIGNSDQEMQ QLNLEGKNYC
101  TAKTLYISDS DKRKHFMLSV KMFYGNSDDI GV FLSKRIK VISKPSKKKQ
151  SLKNADLCIA SGTKVALFNR LRSQTVSTRY LHVEGGNFHA SSQQWGAFFI
201  HLLDDDESEG EEFTVRDGYI HYGQTVKLVC SVTGMALPRL IIRKVDKQTA
251  LLDADDPVSQ LHKCAFYLKD TER MYLCLS QERIIQFQAT PCPKEPNKEM
301  INDGASWTII STDKAEYTFY EGMGPVLAPV TPVPVVESLQ LNGGGDVAML
351  ELTGQNFTPN LRVWFGDVEA ETMYRCGESM LCVVPDISAF REGWRWVRQP
401  VQVPVTLVRN DGIIYSTSLT FTYTPEPGP


References
Data are analyzed by array design with AMADID # 015681 in Del Bianco et al., PLoS ONE 2010


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