-Genomic Data Links
Protein
Hic1
UniPROBE Accession Number
UP00035
Species
Mus musculus
Domain
zf-C2H2
Name and Synonyms
hypermethylated in cancer 1
AA408311, Hic-1, HIC-1, Hypermethylated in cancer 1 protein
Description
Mus musculus hypermethylated in cancer 1 (Hic1)
-PBM Motif Data for Hic1
Primary Motif (Seed-And-Wobble)
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Primary PWM
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Top Kmer
ATGCCA.CC E.S. 0.498
GG.TGGCAT E.S. 0.498
Secondary Motif (Seed-And-Wobble)
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Secondary PWM
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Top Kmer
GTGCCCAA E.S. 0.488
TTGGGCAC E.S. 0.488
Motif (BEEML-PBM) (AMADID # 015681)   (clone pTH2816)
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PWM
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Consensus
NRTGCCMNBN
NVNKGGCAYN
Motif (BEEML-PBM) (AMADID # 016060) (clone pTH2816)
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PWM
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Consensus
RTGCCMNYNN
NNRNKGGCAY
Downloads
Download the zip of all Hic1 PBM files or view the downloads directory for individual files.
Link to TFBSshape
This link will take you to the corresponding entry for Hic1 in TFBSshape, a database which provides information about the shape of the DNA at transcription factor binding sites.

http://rohslab.cmb.usc.edu/TFBSshape/?tfid=&geneID=35&sourceDB=uniprobe

-Hic1 Datasets
Clone ID Expression Array Version Expression Protocol Clone Type Last Modified Save View
pTH2816 #1 AMADID #016060 E. coli DNA binding domain only 2014-08-13 save search
Clone ID Expression Array Version Expression Protocol Clone Type Last Modified Save View
pTH2816 #1 AMADID #015681 E. coli DNA binding domain only 2014-08-13 save search
Clone pTH2816 insert sequence
1    PHLAYGEPES FGDNLYVCIP CGKGFPSSEQ LNAHVEAHVE EEEALYGRAE
51   AAEVAAGAAG LGPPFGGGGD KVTGAPGGLG ELLRPYRCAS CDKSYKDPAT
101  LRQHEKTHWL TRPYPCTICG KKFTQRGTMT RHMRSHLGLK PFACDACGMR
151  FTRQYRLTEH MRIHSGEKPY ECQVCGGKFA QQRNLISHMK MHAVGGAAGA
201  AGALAGL

DNA Binding Domains (Pfam) for clone 2816
Region 86..108
1   YRCASCDKSY KDPATLRQHE KTH

Region 114..136
1   YPCTICGKKF TQRGTMTRHM RSH

Region 142..164
1   FACDACGMRF TRQYRLTEHM RIH

Region 170..192
1   YECQVCGGKF AQQRNLISHM KMH
References
Data are analyzed by array designs with AMADID #s 016060, 015681 in Badis et al., Science 2009


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