-Genomic Data for HOXC4 Links
Protein
HOXC4
UniPROBE Accession Number
UP00596
Species
Homo sapiens
Domain
Homeobox
Name and Synonyms
Name: homeobox protein Hox-C4.
Synonyms:cp19, Homeobox protein CP19, Homeobox protein Hox-3E, Homeobox protein Hox-C4, HOX3, HOX3E
Description
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC4, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants that encode the same protein have been described for HOXC4. Transcript variant one includes the shared exon, and transcript variant two includes only gene-specific exons.
HOXC4 DNA binding domain
1   KRSRTAYTRQ QVLELEKEFH YNRYLTRRRR IEIAHSLCLS ERQIKIWFQN
51  RRMKWKK
-PBM Motif Data for HOXC4_REF_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
TTAATTAA E.S. 0.499
TTAATTAA E.S. 0.499
Downloads
Download the zip of all HOXC4_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXC4_REF_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
AT.AT.ATTA E.S. 0.496
TAAT.AT.AT E.S. 0.496
Downloads
Download the zip of all HOXC4_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXC4_N178S_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
TTAATTAA E.S. 0.497
TTAATTAA E.S. 0.497
Downloads
Download the zip of all HOXC4_N178S PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXC4_N178S_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
TTAATTAA E.S. 0.499
TTAATTAA E.S. 0.499
Downloads
Download the zip of all HOXC4_N178S PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXC4_R158L_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
TTAATTAA E.S. 0.499
TTAATTAA E.S. 0.499
Downloads
Download the zip of all HOXC4_R158L PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXC4_R158L_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
G.TAATTA.C E.S. 0.499
G.TAATTA.C E.S. 0.499
Downloads
Download the zip of all HOXC4_R158L PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
Download Data for HOXC4 (all alleles)
Downloads
Download the zip of all HOXC4 PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-HOXC4 Datasets
Clone Clone Type Last Modified Save View
HOXC4_REF DNA binding domain only search save
HOXC4_REF Insert Sequence
1   HVSTVNPSYN GGEPKRSRTA YTRQQVLELE KEFHYNRYLT RRRRIEIAHS
51  LCLSERQIKI WFQNRRMKWK KDHRLPNTKV RSAPPA



HOXC4_N178S DNA binding domain only search save
HOXC4_N178S Insert Sequence
1   HVSTVNPSYN GGEPKRSRTA YTRQQVLELE KEFHYSRYLT RRRRIEIAHS
51  LCLSERQIKI WFQNRRMKWK KDHRLPNTKV RSAPPA



HOXC4_R158L DNA binding domain only search save
HOXC4_R158L Insert Sequence
1   HVSTVNPSYN GGEPKLSRTA YTRQQVLELE KEFHYNRYLT RRRRIEIAHS
51  LCLSERQIKI WFQNRRMKWK KDHRLPNTKV RSAPPA



References
Data are analyzed by array designs with AMADID #s 030236, 015681 in Barrera et al., Science 2016


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