-Genomic Data for SIX6 Links
Protein
SIX6
UniPROBE Accession Number
UP00620
Species
Homo sapiens
Domain
Homeobox
Swiss-Prot
Q6P051
Name and Synonyms
Name: homeobox protein SIX6.
Synonyms:Homeobox protein SIX6, Homeodomain protein OPTX2, MCOPCT2, Optic homeobox 2, OPTX2, Sine oculis homeobox homolog 6, Six9, SIX9
IHOP
90753
Description
The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2). [provided by RefSeq, Jul 2008]
NCBI RefSeq
NP_031400
SIX6 DNA binding domain
1   EQKTHCFKER TRHLLREWYL QDPYPNPSKK RELAQATGLT PTQVGNWFKN
51  RRQRDRA
JASPAR
None Available
-PBM Motif Data for SIX6_REF_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
AGGTATCA E.S. 0.493
TGATACCT E.S. 0.493
Downloads
Download the zip of all SIX6_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for SIX6_REF_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
GTATCA.T.A E.S. 0.493
T.A.TGATAC E.S. 0.493
Downloads
Download the zip of all SIX6_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for SIX6_H141N_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
AGGTATCA E.S. 0.493
TGATACCT E.S. 0.493
Downloads
Download the zip of all SIX6_H141N PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for SIX6_H141N_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
AGGTATCA E.S. 0.491
TGATACCT E.S. 0.491
Downloads
Download the zip of all SIX6_H141N PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for SIX6_T165A_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
TGATATCA E.S. 0.491
TGATATCA E.S. 0.491
Downloads
Download the zip of all SIX6_T165A PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for SIX6_T165A_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
GGGTATCA E.S. 0.495
TGATACCC E.S. 0.495
Downloads
Download the zip of all SIX6_T165A PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
Download Data for SIX6 (all alleles)
Downloads
Download the zip of all SIX6 PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-SIX6 Datasets
Clone Clone Type Last Modified Save View
SIX6_REF DNA binding domain only search save
SIX6_REF Insert Sequence
1   FPLPRTIWDG EQKTHCFKER TRHLLREWYL QDPYPNPSKK RELAQATGLT
51  PTQVGNWFKN RRQRDRAAAA KNRLQQQVLS Q


SIX6_H141N DNA binding domain only search save
SIX6_H141N Insert Sequence
1   FPLPRTIWDG EQKTHCFKER TRNLLREWYL QDPYPNPSKK RELAQATGLT
51  PTQVGNWFKN RRQRDRAAAA KNRLQQQVLS Q


SIX6_T165A DNA binding domain only search save
SIX6_T165A Insert Sequence
1   FPLPRTIWDG EQKTHCFKER TRHLLREWYL QDPYPNPSKK RELAQAAGLT
51  PTQVGNWFKN RRQRDRAAAA KNRLQQQVLS Q


References
Data are analyzed by array designs with AMADID #s 030236, 015681 in Barrera et al., Science 2016


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